Structure of PDB 5gie Chain A Binding Site BS01
Receptor Information
>5gie Chain A (length=251) Species:
10116
(Rattus norvegicus) [
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KDSLRPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMDGSSVTL
DLSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIE
VIMLRSNQSFTMDDMSWDCGSQDYKYDVTDVSHTLELIEPLIKFQVGLKK
LNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHP
PPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVF
G
Ligand information
>5gie Chain C (length=10) Species:
9606
(Homo sapiens) [
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NHPMLMNLLK
Receptor-Ligand Complex Structure
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PDB
5gie
Regulation of the vitamin D receptor by vitamin D lactam derivatives.
Resolution
2.387 Å
Binding residue
(original residue number in PDB)
I238 K242 S252 Q255 I256 K260 P412 E416
Binding residue
(residue number reindexed from 1)
I73 K77 S87 Q90 I91 K95 P244 E248
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0004879
nuclear receptor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:5gie
,
PDBe:5gie
,
PDBj:5gie
PDBsum
5gie
PubMed
27500498
UniProt
P13053
|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)
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