Structure of PDB 5ggi Chain A Binding Site BS01

Receptor Information
>5ggi Chain A (length=394) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVP
VAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGL
RGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFF
SFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVL
RRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGI
VGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAE
VLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLD
VRGNHRGLWRLFRKKNHFLVVGVPASPYSVKKPPSVTPIFLEPP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5ggi Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of alpha-dystroglycan
Resolution2.6 Å
Binding residue
(original residue number in PDB)		R317 F501 I503 H513 K518 K519
Binding residue
(residue number reindexed from 1)		R64 F248 I250 H260 K265 K266
Enzymatic activity
Catalytic site (original residue number in PDB) D395 D476
Catalytic site (residue number reindexed from 1) D142 D223
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0008375 acetylglucosaminyltransferase activity
Biological Process
GO:0006486 protein glycosylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5ggi, PDBe:5ggi, PDBj:5ggi
PDBsum5ggi
PubMed27493216
UniProtQ8WZA1|PMGT1_HUMAN Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (Gene Name=POMGNT1)

[Back to BioLiP]