Structure of PDB 5g3w Chain A Binding Site BS01
Receptor Information
>5g3w Chain A (length=369) Species:
517
(Bordetella) [
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HAIGYVWNTLYGWVDTGTGSLAAANLTARMQPISHHLAHPDTKRRFHELV
CASGQIEHLTPIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGI
TMMGNGGLEIARLSAGGAVELTRRVATGELSAGYALVNPPGHHAPHNAAM
GFCIFNNTSVAAGYARAVLGMERVAILDWDVHHGNGTQDIWWNDPSVLTI
SLHQHLCFPPDSGYSTERGAGNGHGYNINVPLPPGSGNAAYLHAMDQVVL
PALRAYRPQLIIVGSGFDASMLDPLARMMVTADGFRQMARRTIDCAADIC
DGRIVFVQEGGYSPHYLPFCGLAVIEELTGVRSLPDPYHEFLAGMGGNTL
LDAERAAIEEIVPLLADIR
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
5g3w Chain A Residue 370 [
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Receptor-Ligand Complex Structure
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PDB
5g3w
Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors.
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
D180 H182 D268
Binding residue
(residue number reindexed from 1)
D180 H182 D268
Annotation score
1
Enzymatic activity
Enzyme Commision number
3.5.1.-
Gene Ontology
Molecular Function
GO:0004407
histone deacetylase activity
GO:0016787
hydrolase activity
GO:0046872
metal ion binding
Biological Process
GO:0000122
negative regulation of transcription by RNA polymerase II
GO:0006338
chromatin remodeling
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Molecular Function
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Biological Process
External links
PDB
RCSB:5g3w
,
PDBe:5g3w
,
PDBj:5g3w
PDBsum
5g3w
PubMed
27756124
UniProt
Q70I53
|HDAH_ALCSD Histone deacetylase-like amidohydrolase (Gene Name=hdaH)
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