Structure of PDB 5fwt Chain A Binding Site BS01

Receptor Information
>5fwt Chain A (length=293) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLG
EHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNP
PPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYG
EAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPD
FPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVL
ARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5fwt Chain A Residue 1326 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5fwt Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Y234 D263 D266 D306 N309
Binding residue
(residue number reindexed from 1)		Y205 D234 D237 D277 N280
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5fwt, PDBe:5fwt, PDBj:5fwt
PDBsum5fwt
PubMed27524201
UniProtQ96MU8|KREM1_HUMAN Kremen protein 1 (Gene Name=KREMEN1)

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