Structure of PDB 5fws Chain A Binding Site BS01

Receptor Information
>5fws Chain A (length=288) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLG
EHNYCRNPDGDVSPWCYVGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTG
TSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAAST
ECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTY
ATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHG
RSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5fws Chain A Residue 1327 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5fws Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf
Resolution1.9 Å
Binding residue
(original residue number in PDB)		Y234 D263 D266 D306 N309
Binding residue
(residue number reindexed from 1)		Y200 D229 D232 D272 N275
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5fws, PDBe:5fws, PDBj:5fws
PDBsum5fws
PubMed27524201
UniProtQ96MU8|KREM1_HUMAN Kremen protein 1 (Gene Name=KREMEN1)

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