Structure of PDB 5fk7 Chain A Binding Site BS01

Receptor Information
>5fk7 Chain A (length=624) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGS
IHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDI
RGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDD
GASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSIT
NATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESY
GEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQ
NHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSV
GWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWS
TKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTP
FSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLT
VVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYAN
DEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPAR
PANTSQGLVWDGPTAAMYGLFAGY
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain5fk7 Chain C Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5fk7 Structural Analysis of Beta-Fructofuranosidase from Xanthophyllomyces Dendrorhous Reveals Unique Features and the Crucial Role of N-Glycosylation in Oligomerization and Activity
Resolution2.05 Å
Binding residue
(original residue number in PDB)		E303 E334 H343
Binding residue
(residue number reindexed from 1)		E262 E293 H302
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) A80 E303
Catalytic site (residue number reindexed from 1) A39 E262
Enzyme Commision number 3.2.1.26: beta-fructofuranosidase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5fk7, PDBe:5fk7, PDBj:5fk7
PDBsum5fk7
PubMed26823463
UniProtJ7HDY4

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