Structure of PDB 5fgn Chain A Binding Site BS01

Receptor Information
>5fgn Chain A (length=536) Species: 491 (Neisseria meningitidis serogroup B) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKLGSSALIAFLSLYSSLVLNYAFFAKVVELHPFNGTGADIFLYTMPVVL
FFLSNFVFHVIALPFVHKVLIPLILVISAAVSYQEIFFNIYFNKSMLNNV
LQTTAAESARLITPGYVLWIVCLGVLPALAYIAVKVKYRVWYKEFLTRLV
LAAVSFLCALGIAMLQYQDYASFFRNNKSVTHLIVPSNFIGAGVSKYKDW
KRSNIPYTQLDMAVVQNRPAGSLRRFVVLVVGETTRAANWGLNGYSRQTT
PLLAARGDEIVNFPQVRSCGTSTAHSLPCMFSTFDRTDYDEIKAEHQDNL
LDIVQRAGVEVTWLENDSGCKGVCGKVPNTDVTSLNLPEYCRNGECLDNI
LLTKFDEVLNKNDKDAVLILHTIGSHGPTYYERYTEAERKFTPTCDTNEI
NKCTRATLVNTYDNTVLYVDQFIDKVIRKLENRDDLESVVHYVSDHGESL
GENGMYLHAAPYAIAPSGQTHIPMVMWFSKAFRQHGGIDFQCLKQKAAEN
EYSHDHYFSTVLGLMDISNSQTYRKEMDILAACRRP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5fgn Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5fgn Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		E240 T280 D452 H453
Binding residue
(residue number reindexed from 1)		E233 T273 D445 H446
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016776 phosphotransferase activity, phosphate group as acceptor
GO:0046872 metal ion binding
Biological Process
GO:0009244 lipopolysaccharide core region biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5fgn, PDBe:5fgn, PDBj:5fgn
PDBsum5fgn
PubMed28193899
UniProtQ7DD94

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