Structure of PDB 5ffj Chain A Binding Site BS01

Receptor Information
>5ffj Chain A (length=1044) Species: 1358 (Lactococcus lactis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKLRDYQQTAKENALAHFKENDRGQLIMAPGTGKTFTSLKISEALSKDKN
GPFKVLYLVPSIQLLTQTLRGWNNDTELTITSMAVTSDRDASRGKASDIG
YPATTSSKKILQNWHDFESLPKQTDMLVVFSTYQSIEVIGEAQKEGFPEF
DFIISDEAHRSAFSKVHSNNNVKGLKRMYQTATPKIYILLSSMDDESKYG
EVFFRMGFGQAVSRDINWSKDVAKIAERQINWIKNKLSKDPISLEFKKFV
SSLQHNINDSIDEKQAAEMLSQHLITKPIFEALFSEYSFVNQNPVSQAME
SIVSELEKAGFAKEQENLEPLYESVRMRAEGIEDKQKIIVTLYDKFFKTA
FKIVFTPIEVVDFIVHSVDDVLKKHFGKSLASKDVHILDPFTGTGTFIVR
TLTYLKEQMDAGEISLSDITRKFMKELHANEIVLLSYYIAAINIEATFDE
IYVPFEGIVLTDTFESTETEEDDYFGTNDERLKRQQEVPITAIIGNPPYS
KGQSNENDNNKNIEYPRLFKSIADSYVKNSKTTSVLGMYDSYVLSIRWAS
NRLNDKGVIGFVSNGSYIDSQSADGLRKSLFKEFNHLYIFNLRGDQRTQG
ETSRKEGGKIFGSGSRTSIAISILVKDDSDNHEVHYHDIGDYLTRDDKLD
ILRDKESILNIDWENISPDENNDWINQRDQNYLNYRPLADENGSIFSVKD
IGIVTNRDAWVSNFSKINVSDNVQIMIKNYNLEVDRLENIDVKLNDKTVV
DYVTNDERKISWSRSLKQRAARREKTQFSHSDIMLAMYRPFTKKYLYRNR
FLNENVRKTYQTFPDKNSKNLLINISGQGDKADFATLISEYLSDMHVIGG
QARNLPRFTYETDGRTDNIVSDDEFYYVYGVLHSSAYRKRYANDLKKDLP
RIPLLKNKDKYVEIGRKLSDLHLNYENQPIWDGIEVEISQPDYRVKKMKH
PKKGVLDTIIYNESITIKNIPERAYEYVVNGRPAIEWIIDQYQVKTDKKS
GITDDPNEFSDNPKYILNLLLSVITVSMRTLELIEELPEFEIQE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5ffj Structural insights into DNA sequence recognition by Type ISP restriction-modification enzymes
Resolution2.84 Å
Binding residue
(original residue number in PDB)		V867 N1018 P1019 Y1021 K1023 T1054 S1056 N1086 S1088 S1092 Q1093 S1094 R1119 K1131 G1136 S1137 R1138 R1329 Q1350 M1367 G1372 Q1373 K1473
Binding residue
(residue number reindexed from 1)		V354 N496 P497 Y499 K501 T532 S534 N564 S566 S570 Q571 S572 R597 K609 G614 S615 R616 R807 Q828 M845 G850 Q851 K947
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5ffj, PDBe:5ffj, PDBj:5ffj
PDBsum5ffj
PubMed26975655
UniProtQ93R01

[Back to BioLiP]