Structure of PDB 5fcf Chain A Binding Site BS01

Receptor Information
>5fcf Chain A (length=397) Species: 190485 (Xanthomonas campestris pv. campestris str. ATCC 33913) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALL
IGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQL
PVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTA
IRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQL
VRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDT
GCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEA
VDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQ
PGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5fcf Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		H142 R146 A152 I153
Binding residue
(residue number reindexed from 1)		H140 R144 A150 I151
Enzymatic activity
Catalytic site (original residue number in PDB) H234 D251 D262 T264 H327 H331 H338 E360 V364 R372 E374
Catalytic site (residue number reindexed from 1) H232 D249 D260 T262 H325 H329 H336 E358 V362 R370 E372
Enzyme Commision number 3.4.13.9: Xaa-Pro dipeptidase.
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5fcf, PDBe:5fcf, PDBj:5fcf
PDBsum5fcf
PubMed27816563
UniProtQ8P839

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