Structure of PDB 5fa3 Chain A Binding Site BS01

Receptor Information
>5fa3 Chain A (length=273) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPW
IEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGC
DVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAH
VAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATL
RCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPS
GQEQRYTCHVQHEGLPKPLTLRW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5fa3 Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
Resolution1.86 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 H70 T73 D77 Y84 R97 Y99 Y116 T143 K146 W147 V152 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 E62 K65 V66 H69 T72 D76 Y83 R96 Y98 Y115 T142 K145 W146 V151 L155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5fa3, PDBe:5fa3, PDBj:5fa3
PDBsum5fa3
PubMed28179428
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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