Structure of PDB 5f0o Chain A Binding Site BS01

Receptor Information
>5f0o Chain A (length=1018) Species: 381046 (Lachancea thermotolerans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAAAAAAAAAAAAAAAALERYRADLIDRKILRNKDHGVRAFAACCLSDIL
RLYAPDAPYTDKELTEIFRLFLAQLKLLQEPENGYLTQQTYLINNLLEYR
SIVILTDLPSSSQLVEELFNIFYSPTNSTIQGNMFTAIGGILGEVISECD
SLPMSALKMVFNKFLSHKRAESLDGIPGFEISLIICQTYSNRLGRHFIKF
YSEIMYEVLGEASSAYKTLVKIGNLTSELWKYAPELVGSVTGLLYQLLCS
DNELFRESATKCVSKMLGTHSLINFAVAHSDTYKIWLSKMADISPHVRQA
WVSEIPSILMSRSDLSDDISKGLAKALIDSDHTVRLSAIQTFHEVPVKRL
WECLPNAAVFAGLVHLTRETRRDLRDECIDAVARIYTESIESIPKTNENK
EIWGVVETIPSACFNLYYINDLEINMKVDLLTFEKFLPLGLSNEEFVQRL
LTLLQGFNEKAFSSFYAFNRRQDQMSTVLWKFIEFCEETNSQSPAASLSD
TKLIKTVEWISSGFPSHLNVEQILLAFRELNDRRLYRLIKVAVAETSKHL
TVRNAVSELFKRLEEPELFRKKNIKIESRFTRDNFSTVFRVLIYRAAPII
FNISNLPSFLNTSNEDEKALKRQLIDNISIIKPGIFKDQVKNLVTIITTL
SLAEAMRTVYKISKTFFFQKLEDYAKEGNPLEAKYAIKLLGLAPNAAEYL
SEVATAILPLDLKSKHFASNVLVLAEITKMQPQLLEKDSTEIVGLLIKDV
LLSNDVVGDEDDQQAWFSDEDIYTGKADALSAKVFSLKLFANKIKVMAMT
HAFTERTLKLFFYLVASGGELVSESNTDNYPTPANYQNKLRCCAGLHILK
ITKIAFIKPQDISKLMNLVEDESLEVRSSFIGRLKDFLGDGSISIKFLPL
VFFTAYEPDQALRTSTKMWINYTLSKENFRKGTFFERALPRLIHFIAHHP
DVAEGLRLLTGLTTAIDYLVFYADSVLKASNLALLYYLAGRVRQYAAAAA
AAAAAAAAAAAAAAAAAA
Ligand information
>5f0o Chain E (length=17) Species: 559295 (Lachancea thermotolerans CBS 6340) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SQYLLQDAVTEREVLLV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5f0o Crystal Structure of the Cohesin Gatekeeper Pds5 and in Complex with Kleisin Scc1.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		D404 R410 R443 T445 R446 Y493 I494 K535 F543 D995 D999 M1027 Y1031
Binding residue
(residue number reindexed from 1)		D329 R335 R368 T370 R371 Y418 I419 K460 F468 D886 D890 M918 Y922
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007064 mitotic sister chromatid cohesion

View graph for
Biological Process
External links
PDB RCSB:5f0o, PDBe:5f0o, PDBj:5f0o
PDBsum5f0o
PubMed26923598
UniProtC5DGP8

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