Structure of PDB 5ez1 Chain A Binding Site BS01

Receptor Information
>5ez1 Chain A (length=231) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKSDFDMIKEKEKEALIDQAIRTALVENEAKTEKLDSTPEFKAMMEAVKK
QALVEFWAKKQAEEVKKVQIPEKEMQDFYNANKDQLFVKQEAHARHILVK
TEDEAKRIISEIDKQPKAKKEAKFIELANRDTIDPNSKNAQNGGDLGKFQ
KNQMAPDFSKAAFALTPGDYTKTPVKTEFGYHIIYLISKDSPVTYTYEQA
KPTIKGMLQEKLFQERMNQRIEELRKHAKIV
Ligand information
Ligand IDICB
InChIInChI=1S/C9H7NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h1-5,10H,(H,11,12)
InChIKeyHCUARRIEZVDMPT-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)c2cc1ccccc1n2
OpenEye OEToolkits 1.9.2c1ccc2c(c1)cc([nH]2)C(=O)O
CACTVS 3.385OC(=O)c1[nH]c2ccccc2c1
FormulaC9 H7 N O2
Name1H-indole-2-carboxylic acid
ChEMBLCHEMBL278390
DrugBank
ZINCZINC000000145536
PDB chain5ez1 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ez1 Helicobacter pylori cell binding factor 2: Insights into domain motion.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H161 D199 M219 F223 F244
Binding residue
(residue number reindexed from 1)		H96 D134 M154 F158 F179
Annotation score1
Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:5ez1, PDBe:5ez1, PDBj:5ez1
PDBsum5ez1
PubMed26850168
UniProtP56112|Y175_HELPY Putative peptidyl-prolyl cis-trans isomerase HP_0175 (Gene Name=HP_0175)

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