Structure of PDB 5eyf Chain A Binding Site BS01

Receptor Information
>5eyf Chain A (length=241) Species: 333849 (Enterococcus faecium DO) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDILERSKSTNEIIWGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKIL
GDNGKTEFVEVTSKTRIPLLKNGNIDAIIATMTITDERKKQVDFSDVYFD
AGQALLVKKGSQIKSVDDLNASTTVLAVKGSTSAANIRQHAPDAKILELE
NYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVGGTFTNEPYGIAI
NKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE
Ligand information
Ligand IDGLU
InChIInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKeyWHUUTDBJXJRKMK-VKHMYHEASA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0C(CC(=O)O)C(C(=O)O)N
OpenEye OEToolkits 1.7.0C(CC(=O)O)[C@@H](C(=O)O)N
CACTVS 3.370N[C@@H](CCC(O)=O)C(O)=O
CACTVS 3.370N[CH](CCC(O)=O)C(O)=O
FormulaC5 H9 N O4
NameGLUTAMIC ACID
ChEMBLCHEMBL575060
DrugBankDB00142
ZINCZINC000001482113
PDB chain5eyf Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5eyf Crystal Structure of Solute-binding Protein from Enterococcus faecium with Bound Glutamate
Resolution1.52 Å
Binding residue
(original residue number in PDB)		S93 R96 T111 T113 R118 T162 D200
Binding residue
(residue number reindexed from 1)		S63 R66 T81 T83 R88 T132 D170
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0046872 metal ion binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5eyf, PDBe:5eyf, PDBj:5eyf
PDBsum5eyf
PubMed
UniProtQ3XZW5

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