Structure of PDB 5eu6 Chain A Binding Site BS01
Receptor Information
>5eu6 Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>5eu6 Chain C (length=9) Species:
32630
(synthetic construct) [
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YLEPGPVTV
Receptor-Ligand Complex Structure
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PDB
5eu6
A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
Resolution
2.02 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 H70 T73 D77 Y84 Y99 T143 K146 W147 Q155 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 H70 T73 D77 Y84 Y99 T143 K146 W147 Q155 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5eu6
,
PDBe:5eu6
,
PDBj:5eu6
PDBsum
5eu6
PubMed
26917722
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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