Structure of PDB 5erj Chain A Binding Site BS01

Receptor Information
>5erj Chain A (length=173) Species: 9796 (Equus caballus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSQIRQNYSTEVEAAVNRLVNLYLRASYTYLSLGFYFDRDDVALEGVCHF
FRELAEEKREGAERLLKMQNQRGGRALFQDLQKPSQDEWGTTLDAMKAAI
VLEKSLNQALLDLHALGSAQADPHLCDFLESHFLDEEVKLIKKMGDHLTN
IQRLVGSQAGLGEYLFERLTLKH
Ligand information
Ligand IDCPT
InChIInChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
InChIKeyLXZZYRPGZAFOLE-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6[NH3][Pt]([NH3])(Cl)Cl
ACDLabs 12.01[Pt](N)(N)(Cl)Cl
CACTVS 3.385N|[Pt](|N)(Cl)Cl
FormulaCl2 H6 N2 Pt
NameCisplatin;
diammine(dichloro)platinum
ChEMBL
DrugBankDB00515
ZINC
PDB chain5erj Chain A Residue 218 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5erj Cisplatin encapsulation within a ferritin nanocage: a high-resolution crystallographic study.
Resolution1.45 Å
Binding residue
(original residue number in PDB)		R64 H132
Binding residue
(residue number reindexed from 1)		R64 H132
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005776 autophagosome
GO:0031410 cytoplasmic vesicle
GO:0044754 autolysosome
GO:0070288 ferritin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5erj, PDBe:5erj, PDBj:5erj
PDBsum5erj
PubMed26888424
UniProtP02791|FRIL_HORSE Ferritin light chain (Gene Name=FTL)

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