Structure of PDB 5eqn Chain A Binding Site BS01

Receptor Information
>5eqn Chain A (length=270) Species: 359131 (Streptomyces rubellomurinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EILKKPVTGRSVWQRAQVEDASQWTYVLDEGMRAEILEAAERINEQGLTV
WDLDRKAVPLERAGKLVAQCVEQLEHGFGLAMLRGVPTEGLTVAESQVVM
GVVGLHLGTAVAQNGHGDRVVSIPWHSDAPDIAALLCLTQEFHVASAMHI
YNTLLQEAPELLGLYYAGVFFDYRGEEPPGEPPAYRNAIFGYHNGQLSCR
YFLRNFADSGTAKLGFEQPEVEKLALDTFEEIASRPENHVSMRLEPGDMQ
LVDDNVTVHRRHLLRLWINV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5eqn Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5eqn Structural analysis of a phosphonate hydroxylase with an access tunnel at the back of the active site.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H150 H288
Binding residue
(residue number reindexed from 1)		H126 H259
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.-
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5eqn, PDBe:5eqn, PDBj:5eqn
PDBsum5eqn
PubMed27139827
UniProtQ0ZQ39|FRBJ_STRR3 FR-33289 synthase (Gene Name=frbJ)

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