Structure of PDB 5ek8 Chain A Binding Site BS01

Receptor Information
>5ek8 Chain A (length=668) Species: 41431 (Rippkaea orientalis PCC 8801) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSTKTKTIFDEIKAALVLKVIDSPLGRKLIEEKAEKQVSKTQEAITKPIE
QLNKATGQLLFSDTNKPLHNIELEVWDRDVGTPSDYLGKGVTDQNGRFEI
YYDPEKAGFKDAPDLELRVIDNRVTFDSDNQPVYTNRIAYIIKGGDNVTQ
KTYDFGTLTVPYWPYDPNSPFARIFMPNPEETPDDYSVGRKFQAYASANV
LTPIKAKHTIANTLNPKEPSLTQIQADYPPNLTINLDREKPGYTRSDEYF
VLRVLNGMNPCLLKRSKSDPNQFKMSFIWDNYEKDTEHDLHNVEAYFVLK
DGKLFPTMITIQSRYPDSLAPHSPLKDREVYTPNDGEKWLQAKRIFRTAA
LFDGEAIEHYAKAHVQMEQYAVACFRNLRKNPIRLMLTPHLKSIININRR
GDDLLVEPNLGLFVTNGPLTYPGFLQMCTEVVATYDWKDWQPRQPICDDH
KYAKAANLYWQILTEYVDAFFAKHQQAIADEWVEIRRFSEDLVEHSMPYQ
PIEGIMANTDSDYEWYDTGELDKPDLPRATFNGKTKVIRPITNSNQPSAT
DIDNLKQCCRHIIFHTTLWHTWVNDSQSDEGGELAYNSLALRNGSFGSET
DPNIAPDPIEATNQVYIFSVLNGIKYGLLVKNEDDDVPEELRTALLNRKD
QFAELGIDIGNIRTLINI
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain5ek8 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ek8 Crystal structure of a lipoxygenase from Cyanothece sp. may reveal novel features for substrate acquisition.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H359 H364 H570 N574 I668
Binding residue
(residue number reindexed from 1)		H359 H364 H570 N574 I668
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
Biological Process
GO:0034440 lipid oxidation

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:5ek8, PDBe:5ek8, PDBj:5ek8
PDBsum5ek8
PubMed26667668
UniProtB7K2Q5

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