Structure of PDB 5ejk Chain A Binding Site BS01

Receptor Information
>5ejk Chain A (length=269) Species: 11888 (Rous sarcoma virus - Prague C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLREAKDLHTALHIGPRALSKASNISMQQAREVVQTCPHCNSAPALEAGV
NPRGLGPLQIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVA
VQHHWATAIAVMGRPKAIKTDNGSCFTSKSTREWMARWGIAHTTGIPGNS
QGQAMVERANRMMKDKIRVLAEGDGFMKRIPTSKQGEMMAKAMYALNHFE
RGENTKTPIQKHWRPTVLTEGPPVKIRIETGEWEKGWNVLVWGRGYAAVK
NRDTDKVIWVPSRKVKPDI
Ligand information
>5ejk Chain I (length=42) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagtattgcataagacaacagtgcacgaaagaagaagacact
Receptor-Ligand Complex Structure
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PDB5ejk Crystal structure of the Rous sarcoma virus intasome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		S26 M27 Q28 R95 V96 S98 S124 S128 K129
Binding residue
(residue number reindexed from 1)		S26 M27 Q28 R95 V96 S98 S124 S128 K129
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:5ejk, PDBe:5ejk, PDBj:5ejk
PDBsum5ejk
PubMed26887497
UniProtP03354|POL_RSVP Gag-Pol polyprotein (Gene Name=gag-pol)

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