Structure of PDB 5eh1 Chain A Binding Site BS01

Receptor Information
>5eh1 Chain A (length=209) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTA
DIMSIGVNCTQITATECDFTAASAGFPMDFNVTLRLRAELGALHSAWVTM
PWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVHY
WEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKIFRVGHLSN
ISCYETMAD
Ligand information
Ligand IDCYS
InChIInChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
InChIKeyXUJNEKJLAYXESH-REOHCLBHSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](CS)C(O)=O
OpenEye OEToolkits 1.5.0C([C@@H](C(=O)O)N)S
CACTVS 3.341N[C@@H](CS)C(O)=O
ACDLabs 10.04O=C(O)C(N)CS
OpenEye OEToolkits 1.5.0C(C(C(=O)O)N)S
FormulaC3 H7 N O2 S
NameCYSTEINE
ChEMBLCHEMBL863
DrugBankDB00151
ZINCZINC000000895042
PDB chain5eh1 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5eh1 Crystal structure of human interferon-gamma receptor 2 reveals the structural basis for receptor specificity.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		C174 P191 R193
Binding residue
(residue number reindexed from 1)		C145 P162 R164
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5eh1, PDBe:5eh1, PDBj:5eh1
PDBsum5eh1
PubMed27599734
UniProtP38484|INGR2_HUMAN Interferon gamma receptor 2 (Gene Name=IFNGR2)

[Back to BioLiP]