Structure of PDB 5ef6 Chain A Binding Site BS01

Receptor Information
>5ef6 Chain A (length=61) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQN
RRVKEKKVLAK
Ligand information
Receptor-Ligand Complex Structure
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PDB5ef6 Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R217 R220 Y223 R258 Q259 I262 N266 K270
Binding residue
(residue number reindexed from 1)		R1 R4 Y7 R42 Q43 I46 N50 K54
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5ef6, PDBe:5ef6, PDBj:5ef6
PDBsum5ef6
PubMed28473536
UniProtQ92826|HXB13_HUMAN Homeobox protein Hox-B13 (Gene Name=HOXB13)

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