Structure of PDB 5eeq Chain A Binding Site BS01
Receptor Information
>5eeq Chain A (length=103) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
HRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQ
KVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRH
CCT
Ligand information
>5eeq Chain L (length=11) Species:
32630
(synthetic construct) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
SFEGYDNSFPc
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5eeq
Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
R438 R462 K478 H479 Y480 L481 M495 D496
Binding residue
(residue number reindexed from 1)
R13 R37 K53 H54 Y55 L56 M70 D71
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5eeq
,
PDBe:5eeq
,
PDBj:5eeq
PDBsum
5eeq
PubMed
27257138
UniProt
Q14451
|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)
[
Back to BioLiP
]
