Structure of PDB 5e9a Chain A Binding Site BS01

Receptor Information
>5e9a Chain A (length=679) Species: 1591056 (Rahnella sp. R3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKFPLLSSKISGLLHGADYNPEQWLDHPDVLVRDVEMMKEARCNVMSVGI
FSWSALEPEEGRYTFDWMDQVLNRLHENGISVFLATPSGARPAWMSQKYP
QVLRVGRDRVPALHGGRHNHCMSSPVYREKVQLMNGQLAKRYAHHPAVIG
WHISNEYGGECHCDTCQGQFRDWLKARYVTLDALNKAWWSTFWSHTYTDW
SQLESPSPQGENGVHGLNLDWRRFNTDQVTRFCSEEIRPLKAENPALPAT
TNFMEYFNDYDYWKLAGVLDFISWDSYPMWHTRQDDIGLAAYTAMYHDLM
RTLKQGKPFVLMESTPSFTNWQPTSKLKKPGMHILSSLQAVAHGADSVQY
FQWRKSRGSCEKFHGAVVDHVGHIDTRVGREVAELGSILSALAPVAGSRV
EAKVAIIFDWESRWAMDDAMGPRNAGLHYENTVADHYRALWAQGIAVDVI
NADCDLQGYDLVIAPMLYMVREGVGERISAFVQAGGRFVATYWSGIVNET
DLCFLNGFPGPLRPVLGIWAEEIDSLTDEQHNSVAGVEGNALGLSGPYRA
SQLCEVIHLEGAAALATYGDDFYAGNPAVTVNLYGKGQAYYVASRNDQQF
HADFFTALAKEMKLPRAINTPLPEGVTAARRTDGESEFIFLQNYNADNQT
VALPQDYQGNLPRKLTLPAFGCQILTRKI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5e9a Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5e9a Cloning, expression and structural stability of a cold-adapted beta-galactosidase from Rahnella sp. R3.
Resolution2.561 Å
Binding residue
(original residue number in PDB)		C122 C162 C164 C167
Binding residue
(residue number reindexed from 1)		C121 C161 C163 C166
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.23: beta-galactosidase.
Gene Ontology
Molecular Function
GO:0004565 beta-galactosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006012 galactose metabolic process
Cellular Component
GO:0009341 beta-galactosidase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5e9a, PDBe:5e9a, PDBj:5e9a
PDBsum5e9a
PubMed26145832
UniProtA0A0B4U8I5

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