Structure of PDB 5e63 Chain A Binding Site BS01

Receptor Information
>5e63 Chain A (length=293) Species: 771870 (Sordaria macrospora k-hell) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNPWAVVGFIDAEGSFMVRVRKNSKYKTGWLVVAIFSVTVDKKDLFLLES
LKTFFGGLGSIKKSGNSTFSYRIESSEQLTKIILPFFDKYSLITEKLGDY
LLFKKVLELMGTKEHLTQRGLEKIVSLKASINKGLSEELQAAFPQCVPTP
RPEINNKNIPDPFWLAGFVSGDGSFKSILKKSESIKVGFQSILVFQITQH
ARDVKLMESLISYLGCGFIEKDSRGPWLYYTVTNFSDIQGKIIPFFHQYK
IIGSAYGDYQDWCKIALIMQNKNHLTPEGLNEIRALKGGMNKG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5e63 The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
E20 V47 D48 S191 I192 K193 Q197 E227 R231 T240 N241 F242 H281 L282
Binding residue
(residue number reindexed from 1)
E13 V40 D41 S184 I185 K186 Q190 E220 R224 T233 N234 F235 H274 L275
Enzymatic activity
Catalytic site (original residue number in PDB) G178 D179
Catalytic site (residue number reindexed from 1) G171 D172
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:5e63, PDBe:5e63, PDBj:5e63
PDBsum5e63
PubMed26705195
UniProtF7WD42

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