Structure of PDB 5e3x Chain A Binding Site BS01

Receptor Information
>5e3x Chain A (length=489) Species: 2423 (Fervidobacterium islandicum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEELKSYYKRVAKYYSAAALLYWDMQTYMPKDAGPYRAEVLSEIGTYAFK
QITDDALGKLLETAQPQSEIDEKLVYVGKKEYYKYKKVPPELFQEIMITS
TMLEQKWEIAKPRGDFEEVRPLLEKIVDLSRKYADILGYEGEPYNALLDL
YEPGMKAEEVDQIFSKVRDFIVEVLEKIERLPKSEDPFNREIGVDKQKEF
SNWLLHYLKYDFTKGRLDVSAHPFTNPIGLNDVRITTRYIVNDIRNSIYS
TIHEFGHALYALSIPTEFYGLPIGSSASYGFDESQSRFWENVVGRSLAFW
KGIYSKFIEIVPEMRGYSVEELWRAVNRVQRSFIRTEADEVTYNLHIIIR
FEIERELINGELSVKDVPDKWNELYKKYLGLDVPNNTLGCMQDPHWFGGN
FGYFPTYALGNLYAAQIFEKLKEEINFEEVVSAGNFEIIKNFLKEKIHSK
GKMYEPSDLIKIVTGKPLSYESFVRYIKDKYSKVYEIEL
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain5e3x Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5e3x Biochemical and structural characterization of a keratin-degrading M32 carboxypeptidase from Fervidobacterium islandicum AW-1
Resolution2.197 Å
Binding residue
(original residue number in PDB)		H253 H257 E283 S286
Binding residue
(residue number reindexed from 1)		H253 H257 E283 S286
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.17.19: carboxypeptidase Taq.
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0004181 metallocarboxypeptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5e3x, PDBe:5e3x, PDBj:5e3x
PDBsum5e3x
PubMed26603937
UniProtA0A140UHP3

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