Structure of PDB 5e14 Chain A Binding Site BS01

Receptor Information
>5e14 Chain A (length=232) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5e14 Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.22 Å
Binding residue
(original residue number in PDB)
I358 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I52 V70 E74 D222 L223 E226
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5e14, PDBe:5e14, PDBj:5e14
PDBsum5e14
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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