Structure of PDB 5e02 Chain A Binding Site BS01

Receptor Information
>5e02 Chain A (length=964) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IMTDAFQTAESREVTGAQGFAPTEGESIVLSHNIQHQVALPPDLDYEYIP
LSEHKPPAEPARTYSFKLDPFQALSVASIEREESVLVSAHTSAGKTVVAE
YAIAQCLKKNQRVIYTSPIKALSNQKYRDFQAEFGDVGLMTGDVTINPTA
SCLVMTTEILRSMLYRGSEIMREVAWVVFDEIHYMRDKIRGVVWEETIIL
LPDKVRYVFLSATIPNAFQFAEWIAKIHRQACHVVYTDFRPTPLQNYFFP
AGGKGILLIVDEKGNFKENNFNQAMAMIEEKEKADIAKIIKMILKKNFQP
VIVFNFSKRECEQMALASSSMKFNAPDEENMVNKVFENALASLSEDDKNL
PQISNILPLLRKGIGVHHSGLLPILKETIEILFQEGLIKVLFATETFSIG
LNMPARTVVFTQVTKWDGQQRRPLTSSEYIQMAGRAGRRGLDDRGIVIMM
VDDKLEPETARAIVVGNQDKLNSAFHLGYNMVLNLLRIEAISPEYMLERC
FFQFQNAASVPQLERELISLQQERDAIIIPDESIVKDYYGVRQQLEEYNK
DMVFVIQHPQNCLGFFQEGRLIHIKSPSGVDYGWGVLIKHIQRQTPKNGQ
PPYPEQESYVLDVLLKVSGDFNPKTRGEGPMPEGIMPAGKDSKNARWEVV
PCLLNCLRALGQLRVFLPKRLESADEKDGVGKAVDEISRRFPDGIPILDP
MENMGINDDSFKKLLRKIEVLESRLVANPLHNSPLLVELWNQYSLKMQLG
EQIKEKKKAIARAHSVAQLDELKSRKRVLRRLGFINDAEVVQMKARVACE
ISSTEGHELLLAELLFNRFFNELSPEICACILSCFIFDEKIETQALKEEL
AKPFREIQAQARIIAKVSAESKLDVNEDEYVQSLKWQLMETVLAWAQGRP
FSEICKMTNVYEGSLIRLFRRLEELLRQMAEAARVMGSEELKDKFELSLS
KIRRDIVSFNSLYL
Ligand information
Receptor-Ligand Complex Structure
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PDB5e02 Structure of the frequency-interacting RNA helicase: a protein interaction hub for the circadian clock.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		I232 K233 R303 F448 S449 K450 S511 T536 T538 F979 D980 E981 R1063
Binding residue
(residue number reindexed from 1)		I119 K120 R190 F306 S307 K308 S369 T394 T396 F837 D838 E839 R921
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000460 maturation of 5.8S rRNA
GO:0006401 RNA catabolic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5e02, PDBe:5e02, PDBj:5e02
PDBsum5e02
PubMed27340124
UniProtQ1K502

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