Structure of PDB 5dzt Chain A Binding Site BS01

Receptor Information
>5dzt Chain A (length=886) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLINVLSINERCFLLKQSGNEKYDIKNLQAWKERKSVLKQDDLDYLIKYK
YESLDNFGLGITPIENFPDKEVAIQYIKDQSWYIFFESILDSYNDSEEQL
LEVDASYPFRYFLQYARLFLLDLNSELNICTKEFIINLLEILTQELIHLT
SKTLVLDLHRFIYYLKKRFNSKKDIIAFYTCYPELMRITVVRMRYFLDNT
KQMLIRVTEDLPSIQNCFNIQSSELNSISESQGDSHSRGKTVSTLTFSDG
KKIVYKPKINSENKLRDFFEFLNKELEADIYIVKKVTRNTYFYEEYIDNI
EINNIEEVKKYYERYGKLIGIAFLFNVTDLHYENIIAHGEYPVIIDNETF
FQQNIPIEFGNSATVDAKYKYLDSIMVTGLVPKNTPIMNNEKISFISYEK
YIVTGMKSILMKAKDSKKKILAYINNNLQNLIVRNVIRPTQRYADMLEFS
YHPNCFSNAIEREKVLHNMWAYPYKNKKVVHYEFSDLIDGDIPIFYNNIS
KTSLIASDGCLVEDFYQESALNRCLNKINDLCDEDISIQTVWLEIALNIY
NPYKYINDLKNQNSNKYIYTGLELNGKIIQACQKIEKKIFKRAIFNKKTN
TVNWIDIKLDQDWNVGILNNNMYDGLPGIFIFYVALKYITKNHKYDYVIE
CIKNSIYTIPSEDILSAFFGKGSLIYPLLVDYRLNNDINSLNVAVEIADM
DWIHGHNSIIKVLLLLSEITEDEKYRKFSLEIFEKLSEEPYFNFRGFGHG
IYSYVHLLSKFNRIDKANSLLHKIKNNSWCKGTVGELLATDINKTIEYKN
KDCLCHGNAGTLEGLIQLAKKDPETYQYKKNKLISYMLKYFEKNNTLKVA
GSEYLESLGFFVGISGVGYELLRNLDSEIPNALLFE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5dzt Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dzt The enterococcal cytolysin synthetase has an unanticipated lipid kinase fold.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		C875 C911 H912
Binding residue
(residue number reindexed from 1)		C780 C805 H806
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0031179 peptide modification

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5dzt, PDBe:5dzt, PDBj:5dzt
PDBsum5dzt
PubMed26226635
UniProtQ8KUA3

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