Structure of PDB 5dxr Chain A Binding Site BS01

Receptor Information
>5dxr Chain A (length=235) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dxr Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.28 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I55 K59 L69 V73 E77 E229
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dxr, PDBe:5dxr, PDBj:5dxr
PDBsum5dxr
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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