Structure of PDB 5dxp Chain A Binding Site BS01

Receptor Information
>5dxp Chain A (length=222) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDSMMGLLTNLADRELVHMINWAK
RVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYDHI
HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHL
YSMKCKNVVPLSDLLLEMLDAH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dxp Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.201 Å
Binding residue
(original residue number in PDB)
I358 K362 Q375 V376 L379 E380 E542 M543
Binding residue
(residue number reindexed from 1)
I46 K50 Q63 V64 L67 E68 E217 M218
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dxp, PDBe:5dxp, PDBj:5dxp
PDBsum5dxp
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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