Structure of PDB 5dxg Chain A Binding Site BS01
Receptor Information
>5dxg Chain A (length=231) Species:
9606
(Homo sapiens) [
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ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5dxg Chain C (length=11) Species:
9606
(Homo sapiens) [
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HKKLHRKLQDS
Receptor-Ligand Complex Structure
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PDB
5dxg
Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Resolution
1.86 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I52 K56 L66 V70 E74 D221 L222 E225
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5dxg
,
PDBe:5dxg
,
PDBj:5dxg
PDBsum
5dxg
PubMed
26928945
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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