Structure of PDB 5dxe Chain A Binding Site BS01
Receptor Information
>5dxe Chain A (length=231) Species:
9606
(Homo sapiens) [
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ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPLSDLLLEMLDAH
Ligand information
>5dxe Chain C (length=11) Species:
9606
(Homo sapiens) [
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HKLLHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5dxe
Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Resolution
1.5 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I52 K56 L66 Q69 V70 E74 L223 E226
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5dxe
,
PDBe:5dxe
,
PDBj:5dxe
PDBsum
5dxe
PubMed
26928945
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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