Structure of PDB 5dx3 Chain A Binding Site BS01

Receptor Information
>5dx3 Chain A (length=231) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPLSDLLLEMLDAH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dx3 Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Resolution2.0903 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L539 E542
Binding residue
(residue number reindexed from 1)
I52 K56 L66 V70 L223 E226
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dx3, PDBe:5dx3, PDBj:5dx3
PDBsum5dx3
PubMed26928945
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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