Structure of PDB 5dwg Chain A Binding Site BS01

Receptor Information
>5dwg Chain A (length=225) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLL
DRNQGKCVEMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTK
DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGM
EHLYSMKCKNVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dwg Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
I358 V376 L539 E542
Binding residue
(residue number reindexed from 1)
I48 V66 L216 E219
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dwg, PDBe:5dwg, PDBj:5dwg
PDBsum5dwg
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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