Structure of PDB 5dwb Chain A Binding Site BS01

Receptor Information
>5dwb Chain A (length=278) Species: 53501 (Thalassovita gelatinovora) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRLDLDFGRGLVAHVMLDNVSEEQYQQISDYFVPLVNKPKLKSRDAIGQA
FVMATEVCPDANPSDLWHHVLYRIYIREKIGTDPSQSWVRTSGEAFEVAL
VERYNPVLARHGIRLTALFKGQKGLALTRMGVADRVGSRKVDVMIEKQGG
GRSPDAEGFGVVGGIHAKVSLAERVSDDIPASRIMMGEGLLSVLSTLDVK
SFPPPHGDLVNRGELGTPDRPSDKRNYIEGHGDFSACFSYNLRTSPSNAT
TPSGRHIYVSGFSGQDDEFTDYLVAQLA
Ligand information
Receptor-Ligand Complex Structure
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PDB5dwb Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K42 R44 T82 D83 Q86 S87 V89 R90 F119 K120 E173 F202 K224
Binding residue
(residue number reindexed from 1)		K42 R44 T82 D83 Q86 S87 V89 R90 F119 K120 E173 F202 K224
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:5dwb, PDBe:5dwb, PDBj:5dwb
PDBsum5dwb
PubMed28039325
UniProtQ9KHV6|T2A1_THAGE Type II restriction enzyme AgeI (Gene Name=ageIR)

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