Structure of PDB 5dnj Chain A Binding Site BS01
Receptor Information
>5dnj Chain A (length=215) Species:
10090
(Mus musculus) [
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HLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLNYFRNYMSEHLLKAGANITPRELPYLRTWFRTRSAIILHLSNG
TVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELAS
RLRYARTMVDKLLSS
Ligand information
>5dnj Chain B (length=4) Species:
32630
(synthetic construct) [
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tHST
Receptor-Ligand Complex Structure
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PDB
5dnj
Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
W414 D416 Y417 Y421 Y481 Y485 L490 L491 H538 K540
Binding residue
(residue number reindexed from 1)
W42 D44 Y45 Y49 Y109 Y113 L118 L119 H160 K162
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:5dnj
,
PDBe:5dnj
,
PDBj:5dnj
PDBsum
5dnj
PubMed
26459104
UniProt
Q07832
|PLK1_MOUSE Serine/threonine-protein kinase PLK1 (Gene Name=Plk1)
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