Structure of PDB 5dmc Chain A Binding Site BS01

Receptor Information
>5dmc Chain A (length=223) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTK
DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGM
EHLYSMKCKNPLSDLLLEMLDAH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dmc Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.403 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 E380 D538 E542 M543
Binding residue
(residue number reindexed from 1)
I49 K53 V67 E71 D214 E218 M219
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dmc, PDBe:5dmc, PDBj:5dmc
PDBsum5dmc
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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