Structure of PDB 5dir Chain A Binding Site BS01

Receptor Information
>5dir Chain A (length=157) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PDVDRFGRLPWLWITVLVFVLDQVSKAFFQAELSMYQQIVVIPDLFSWTL
AYNTGAAFSFLADSSGWQRWLFALIAIVVSASLVVWLKRLKKGETWLAIA
LALVLGGALGNLYDRMVLGHVVDFILVHWQNRWYFPAFNLADSAITVGAV
MLALDMF
Ligand information
Receptor-Ligand Complex Structure
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PDB5dir Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		N54 F59 N112 R116 D124 D143 I146
Binding residue
(residue number reindexed from 1)		N53 F58 N111 R115 D123 D142 I145
Enzymatic activity
Enzyme Commision number 3.4.23.36: signal peptidase II.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006465 signal peptide processing
GO:0006508 proteolysis
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5dir, PDBe:5dir, PDBj:5dir
PDBsum5dir
PubMed26912896
UniProtQ9HVM5|LSPA_PSEAE Lipoprotein signal peptidase (Gene Name=lspA)

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