Structure of PDB 5da9 Chain A Binding Site BS01

Receptor Information
>5da9 Chain A (length=433) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKIEKLSILGVRSFGPHHPETIAFNTPLTLIVGYNGSGKTTVIECLKYAT
TGELPPNSTRNGAFIHDPDLVGEKEVRAQVKLSFRSTIGESYVVTRNIQL
LVQRNNKRTQKTLEGSLLLRNNGERTVISTRVAELDKLVSEKLGVPPAIL
DAVIFCHQDDSLWPMSEPAALKKRFDEIFEAQKYTKVIENIRLLKKKKGD
ELKILKEREVQDKANKERAEKVDELDLKDAKAKYKETHIKVETTKAAIED
LGRGMAAVDHAIMQYHSKMMEQINRTIAELWQSTYQGTDIDTIQIRSDVE
STTSSTRRNYNYRVSMVKGDTEMDMRGRCSAGQKVLASIIIRLALAESFC
ANCGLIALDEPTTNLDSDNIRSLAESLHGIIKARQAQGNLQLIVITHDEE
FLKYMQCSDFCDDFYRVKRDEKQNSVIVRESIT
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5da9 Chain A Residue 1401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5da9 Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		T41 Q159
Binding residue
(residue number reindexed from 1)		T40 Q158
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.-.-
Gene Ontology
Molecular Function
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006302 double-strand break repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5da9, PDBe:5da9, PDBj:5da9
PDBsum5da9
PubMed26896444
UniProtG0SHW7|RAD50_CHATD DNA repair protein RAD50 (Gene Name=RAD50)

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