Structure of PDB 5d7z Chain A Binding Site BS01

Receptor Information
>5d7z Chain A (length=281) Species: 4577 (Zea mays) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDWHKHDSKRMLHAVYRVGDLDRTIKYYTECFGMKLLRKRDVPDEKYTNA
FLGFGPENTNFAVELTYNYGVDKYDIGTGFGHFAIANDDVYKLAENIKSK
GGKITREPGPVKGGSTVIAFAQDPDGYMFELIQRADTPEPLCQVMLRVGD
LERSIKFYEKALGMKLLRKKDVPDYKYTIAMLGYADEDKTTVLELTYNYG
VTEYSKGNAYAQVAIGTNDVYKSAEAVDLATKELGGKILRQPGPLPGINT
KIASFVDPDGWKVVLVDNTDFLKELHLEHHH
Ligand information
Ligand IDNI
InChIInChI=1S/Ni/q+2
InChIKeyVEQPNABPJHWNSG-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ni++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ni+2]
FormulaNi
NameNICKEL (II) ION
ChEMBL
DrugBankDB14204
ZINC
PDB chain5d7z Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5d7z Structure of the novel monomeric glyoxalase I from Zea mays.
Resolution1.73 Å
Binding residue
(original residue number in PDB)		H290 H295
Binding residue
(residue number reindexed from 1)		H276 H281
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H27 E78 H96 E144
Catalytic site (residue number reindexed from 1) H13 E64 H82 E130
Enzyme Commision number 4.4.1.5: lactoylglutathione lyase.
Gene Ontology
Molecular Function
GO:0004462 lactoylglutathione lyase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5d7z, PDBe:5d7z, PDBj:5d7z
PDBsum5d7z
PubMed26457425
UniProtB6TPH0

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