Structure of PDB 5d6y Chain A Binding Site BS01

Receptor Information
>5d6y Chain A (length=108) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIV
SQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLV
VKRDDVYT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5d6y Reader domain specificity and lysine demethylase-4 family function.
Resolution2.287 Å
Binding residue
(original residue number in PDB)		D934 G935 S936 F937 S938 N940 L941 W967 T968 Y973
Binding residue
(residue number reindexed from 1)		D37 G38 S39 F40 S41 N43 L44 W70 T71 Y76
Enzymatic activity
Enzyme Commision number 1.14.11.66: [histone H3]-trimethyl-L-lysine(9) demethylase.
1.14.11.69: [histone H3]-trimethyl-L-lysine(36) demethylase.
External links
PDB RCSB:5d6y, PDBe:5d6y, PDBj:5d6y
PDBsum5d6y
PubMed27841353
UniProtO75164|KDM4A_HUMAN Lysine-specific demethylase 4A (Gene Name=KDM4A)

[Back to BioLiP]