Structure of PDB 5d0j Chain A Binding Site BS01
Receptor Information
>5d0j Chain A (length=106) Species:
9606
(Homo sapiens) [
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HRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQ
KVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRH
CCTRVA
Ligand information
>5d0j Chain L (length=7) Species:
32630
(synthetic construct) [
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EGYDNSC
Receptor-Ligand Complex Structure
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PDB
5d0j
Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
R438 H479 Y480 L481
Binding residue
(residue number reindexed from 1)
R13 H54 Y55 L56
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5d0j
,
PDBe:5d0j
,
PDBj:5d0j
PDBsum
5d0j
PubMed
27257138
UniProt
Q14451
|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)
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