Structure of PDB 5czw Chain A Binding Site BS01

Receptor Information
>5czw Chain A (length=229) Species: 480520 (Myroides profundi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLKELRAVPKADIVSGFEGAKVCKDVYPKGSTKWPNGSVITVGLYGGTPY
VRSKVKQYAQEWSNYANITFNFVESGTPQIRVTFTQGAGSYSYLGTQALS
IPSNEETMNFGWFDDSTSDTEFSRTVIHEFGHALGMIHEHQHPLTNIPWD
KNKVYAYYAGYPNYWSKKDVDNNLFATYSTTQTQYSAYDTQSIMHYSISS
ALTTNGFSVGNNSVLSATDKQFIATVYPR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5czw Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5czw Myroilysin is a New Bacterial Member of the M12A Family of Metzincin Metallopeptidases and Activated by a Cysteine-switch Mechanism
Resolution1.6 Å
Binding residue
(original residue number in PDB)		C28 H142 H146 H152
Binding residue
(residue number reindexed from 1)		C23 H128 H132 H138
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5czw, PDBe:5czw, PDBj:5czw
PDBsum5czw
PubMed28188295
UniProtB5B0E6

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