Structure of PDB 5cyx Chain A Binding Site BS01

Receptor Information
>5cyx Chain A (length=318) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSPPSFGVNMTLVTLPEDLPVGAVAFWLVATLTYGISGPNASYFSVNANT
GEVKLASPLDFETVPFFKITISTSDGLNIRTAEMQVIVEDRNDNIPVFLN
TEFSTSINETLPVGSVVFSVLAEDKDTGTAGLVQYFIEKVIPSTANSNNL
FRILENGSIVLNDTLSYNNKSAFYQLELKACDSGGILDNKPKTQCSQPVF
VSISVIDEPDLDPRFIREFYSASVAEDATLGTSVLTVEAVDSDKGINDIV
TYSVSNSTRPGWFDIREDGVIFVNGSLDREQLLLENEEVQIQVTATEKNL
NIYGQEAKASMWVTIRVT
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5cyx Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5cyx Crystal Structure of Mouse Protocadherin-24 EC1-3
Resolution2.1 Å
Binding residue
(original residue number in PDB)
E17 D66 E68 D99
Binding residue
(residue number reindexed from 1)
E17 D60 E62 D93
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5cyx, PDBe:5cyx, PDBj:5cyx
PDBsum5cyx
PubMed
UniProtE9Q7P9|CDHR2_MOUSE Cadherin-related family member 2 (Gene Name=Cdhr2)

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