Structure of PDB 5cix Chain A Binding Site BS01

Receptor Information
>5cix Chain A (length=246) Species: 3672 (Momordica balsamina) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVSFRLSGADPSSYGMFIKDLRNALPHTEKVYNIPLLLPSVSGAGRYLLM
HLFNYDGNTITVAVDVTNVYIMGYLALTTSYFFNEPAADLASQYVFRSAR
RKITLPYSGNYERLQIAAGKPREKIPIGLPALDTAISTLLHYDSTAAAGA
LLVLIQTTAEAARFKYIEQQIQERAYRDEVPSSATISLENSWSGLSKQIQ
LAQGNNGVFRTPTVLVDSKGNRVQITNVTSNVVTSNIQLLLNTKNI
Ligand information
Ligand ID211
InChIInChI=1S/C6H15NO3/c8-4-1-7(2-5-9)3-6-10/h8-10H,1-6H2
InChIKeyGSEJCLTVZPLZKY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CO)N(CCO)CCO
ACDLabs 10.04
CACTVS 3.341		OCCN(CCO)CCO
FormulaC6 H15 N O3
Name2,2',2''-NITRILOTRIETHANOL
ChEMBLCHEMBL446061
DrugBankDB13747
ZINCZINC000000896409
PDB chain5cix Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5cix Structure of the complex of type 1 Ribosome inactivating protein with triethanolamine at 1.88 Angstrom resolution.
Resolution1.88 Å
Binding residue
(original residue number in PDB)		V69 Y70 I71 E85 G109 I155
Binding residue
(residue number reindexed from 1)		V69 Y70 I71 E85 G109 I155
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) I71 E160 R163
Catalytic site (residue number reindexed from 1) I71 E160 R163
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016787 hydrolase activity
GO:0030598 rRNA N-glycosylase activity
GO:0090729 toxin activity
Biological Process
GO:0017148 negative regulation of translation
GO:0035821 modulation of process of another organism

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Molecular Function
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Biological Process
External links
PDB RCSB:5cix, PDBe:5cix, PDBj:5cix
PDBsum5cix
PubMed
UniProtD9J2T9

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