Structure of PDB 5ciu Chain A Binding Site BS01
Receptor Information
>5ciu Chain A (length=127) Species:
9606
(Homo sapiens) [
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EYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFG
DGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGK
TFDQLKPMLEWAHGGFKPTGIEGLKPN
Ligand information
>5ciu Chain C (length=7) Species:
9606
(Homo sapiens) [
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TGGVKKP
Receptor-Ligand Complex Structure
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PDB
5ciu
Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B.
Resolution
2.24 Å
Binding residue
(original residue number in PDB)
W246 Q253
Binding residue
(residue number reindexed from 1)
W31 Q38
Enzymatic activity
Enzyme Commision number
2.1.1.37
: DNA (cytosine-5-)-methyltransferase.
External links
PDB
RCSB:5ciu
,
PDBe:5ciu
,
PDBj:5ciu
PDBsum
5ciu
PubMed
26993463
UniProt
Q9UBC3
|DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (Gene Name=DNMT3B)
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