Structure of PDB 5chz Chain A Binding Site BS01

Receptor Information
>5chz Chain A (length=140) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPS
AEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGI
GKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5chz Structure of wild-type human MBD4 bound to a G:T mismatch
Resolution1.83 Å
Binding residue
(original residue number in PDB)		L447 V448 Q449 L466 R468 T469 S470 G471 Y540 D560 K562
Binding residue
(residue number reindexed from 1)		L10 V11 Q12 L29 R31 T32 S33 G34 Y103 D123 K125
Enzymatic activity
Enzyme Commision number 3.2.2.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5chz, PDBe:5chz, PDBj:5chz
PDBsum5chz
PubMed
UniProtO95243|MBD4_HUMAN Methyl-CpG-binding domain protein 4 (Gene Name=MBD4)

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