Structure of PDB 5cg9 Chain A Binding Site BS01
Receptor Information
>5cg9 Chain A (length=267) Species:
5762
(Naegleria gruberi) [
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HMINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHD
GSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYV
TADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALN
NCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLE
LTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKP
YYEDTQKNSLKIHKETK
Ligand information
>5cg9 Chain B (length=11) [
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catgcgctgac
Receptor-Ligand Complex Structure
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PDB
5cg9
Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.
Resolution
2.693 Å
Binding residue
(original residue number in PDB)
S148 M149 P150 K303 K318
Binding residue
(residue number reindexed from 1)
S94 M95 P96 K249 K264
Enzymatic activity
Enzyme Commision number
1.14.11.80
: methylcytosine dioxygenase.
External links
PDB
RCSB:5cg9
,
PDBe:5cg9
,
PDBj:5cg9
PDBsum
5cg9
PubMed
26323320
UniProt
D2W6T1
|TET1_NAEGR Tet-like dioxygenase 1 (Gene Name=TET1)
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