Structure of PDB 5cg8 Chain A Binding Site BS01
Receptor Information
>5cg8 Chain A (length=266) Species:
5762
(Naegleria gruberi) [
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MINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDG
SVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVT
ADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNN
CLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLEL
TDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPY
YEDTQKNSLKIHKETK
Ligand information
>5cg8 Chain B (length=14) [
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agaattccgttcca
Receptor-Ligand Complex Structure
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PDB
5cg8
Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.
Resolution
2.702 Å
Binding residue
(original residue number in PDB)
S148 M149 P150 K318
Binding residue
(residue number reindexed from 1)
S93 M94 P95 K263
Enzymatic activity
Enzyme Commision number
1.14.11.80
: methylcytosine dioxygenase.
External links
PDB
RCSB:5cg8
,
PDBe:5cg8
,
PDBj:5cg8
PDBsum
5cg8
PubMed
26323320
UniProt
D2W6T1
|TET1_NAEGR Tet-like dioxygenase 1 (Gene Name=TET1)
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