Structure of PDB 5cfc Chain A Binding Site BS01

Receptor Information
>5cfc Chain A (length=252) Species: 434309 (Saffold virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVDNAEKGKVSDDNASTDFVAEPVKLPENQTRVSFFYDRSTLSSVLQSTS
DVSSKFTPSTAKNLQNSILLTPLPSDIVNNSVLPEQERWISFASPTTQKP
PYKTKQDWNFIMFSPFTYYKCDLEVTLSKNDRETISSVVRYVPCGAPSDL
SDQTMPQTPSLADTRDPHMWVVGQGTTNQISFVIPYTSPLSVLPSVWFNG
FSNFDNSSRFGVAPNADFGRLLLQGQGTFSVHYRYKKMRVFCPRPTVFIP
WP
Ligand information
>5cfc Chain D (length=24) Species: 434309 (Saffold virus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GNEGVIINNYYSNQYQNSIDLSAN
Receptor-Ligand Complex Structure
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PDB5cfc Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
R32 F35 D38 D128 R242 K245
Binding residue
(residue number reindexed from 1)
R32 F35 D38 D122 R234 K237
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.6.4.13: RNA helicase.
External links
PDB RCSB:5cfc, PDBe:5cfc, PDBj:5cfc
PDBsum5cfc
PubMed27279624
UniProtC0MHL9|POLG_SAFV Genome polyprotein

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