Structure of PDB 5c6d Chain A Binding Site BS01
Receptor Information
>5c6d Chain A (length=311) Species:
9606
(Homo sapiens) [
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AHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLS
QTMGFPQDQIRLWPMQARSNGTKRPAMLADGNKTMIELSDNENPWTIFLE
TVDPTLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM
CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQK
DDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYF
QVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKP
RQPKKLYYQQL
Ligand information
>5c6d Chain C (length=13) Species:
9606
(Homo sapiens) [
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SPRTGKGKWKRKS
Receptor-Ligand Complex Structure
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PDB
5c6d
An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.
Resolution
2.292 Å
Binding residue
(original residue number in PDB)
Q626 A627 R628 S629 N630 E736 E744 D758 E759 M761 D764
Binding residue
(residue number reindexed from 1)
Q66 A67 R68 S69 N70 E166 E174 D188 E189 M191 D194
Enzymatic activity
Enzyme Commision number
3.4.19.12
: ubiquitinyl hydrolase 1.
External links
PDB
RCSB:5c6d
,
PDBe:5c6d
,
PDBj:5c6d
PDBsum
5c6d
PubMed
26299963
UniProt
Q93009
|UBP7_HUMAN Ubiquitin carboxyl-terminal hydrolase 7 (Gene Name=USP7)
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